Also called gum gugal and gugglesterone, guggul is a resin derived from a tree that is native to India. Despite its use by herbalists as a treatment for high cholesterol, triglycerides, arthritis, digestive problems, mouth infections, menstrual problems, obesity and acne, guggul poses a few side effects in some patients.
Side Effects
Side effects associated with long-term guggul use include stomach upset, headaches, nausea, vomiting, diarrhea, restlessness, belching and hiccups.
Features
Side effects from guggul are most common when the supplement is taken in amounts greater than 6,000mg per day, according to RxList.
Drug Interactions
Guggul poses a risk for increased side effects from estrogen supplements or oral contraceptives. When taken with blood-thinning medications like warfarin, guggul poses a risk for sudden, severe bleeding, warns RxList. Guggul may increase the potency of anti-inflammatory pain killers, drugs used to lower blood pressure, muscle relaxants, lithium and diuretics. It may reduce the effects of anti-arrythmic and anti-diabetic drugs.
Risks
Some patients develop serious allergic reactions to guggul, causing shortness of breath, chest pain, hives and swelling, reports the Physicians Desktop Reference.
Considerations
Avoid using guggul while pregnant or nursing. If you have a history of estrogen-dependent cancers, like breast or uterine tumors, fibroids, thyroid disease, or are scheduled for surgery within the next two weeks, it may not be safe for you to use guggul, warns RxList. Guggul should be used with caution by people with liver disease, inflammatory bowel disease and diarrhea.
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